Systematic review of diagnostic tools for peritoneal metastasis in gastric cancer-staging laparoscopy and its alternatives

作     者：Si Ying Adelina Ho Kon Voi Tay 

作者机构：Lee Kong Chian School of MedicineSingapore 308232Singapore Upper GI and Bariatric DivisionGeneral SurgeryTan Tock Seng HospitalSingapore 308433Singapore Upper GI and Bariatric DivisionGeneral SurgeryWoodlands HealthSingapore 768024Singapore 

出 版 物：《World Journal of Gastrointestinal Surgery》 (世界胃肠外科杂志（英文版）（电子版）)

年 卷 期：2023年第15卷第10期

页      面：2280-2293页

核心收录：

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

主　　题：Gastric cancer Peritoneal metastases Computed tomography Positron emission tomography Magnetic resonance imaging Staging laparoscopy 

摘      要：BACKGROUND Gastric cancer is one of the leading causes of cancer burden and mortality,often resulting in peritoneal metastasis in advanced stages with negative survival *** laparoscopy has become standard practice for suspected cases before a definitive gastrectomy or *** systematic review aims to compare the efficacy of other diagnostic modalities instead of staging laparoscopy as the alternatives are able to reduce cost and invasive staging ***,a radiomic model based on computed tomography and positron emission tomography(PET)has also emerged as another method to predict peritoneal *** To determine if the efficacy of computed tomography,magnetic resonance imaging and PET is comparable with staging *** Articles comparing computed tomography,PET,magnetic resonance imaging,and radiomic models based on computed tomography and PET to staging laparoscopies were filtered out from the Cochrane Library,EMBASE,PubMed,Web of Science,and Reference Citations Analysis(https://***/).In the search for studies comparing computed tomography(CT)to staging laparoscopy,five retrospective studies and three prospective studies were ***,five retrospective studies and two prospective studies were also included for papers comparing CT to PET *** one retrospective study and one prospective study were found to be suitable for papers comparing CT to magnetic resonance imaging *** Staging laparoscopy outperformed computed tomography in all measured aspects,namely sensitivity,specificity,positive predictive value and negative predictive *** resonance imaging and PET produced mixed results,with the former shown to be only marginally better than computed *** performed slightly better than PET in most measured domains,except in specificity and true negative *** speculate that this may be due to the limited F-fluorodeoxyglucose uptake in small peri