Factors associated with in-hospital mortality in sepsis patients admitted to the emergency department:A retrospective study

作     者：Song Kun Guo Cuirong He Liudang Su Yingjie Ding Ning Song Kun;Guo Cuirong;He Liudang;Su Yingjie;Ding Ning

作者机构：Department of Emergency MedicineThe Affiliated Changsha Central HospitalHengyang Medical SchoolUniversity of South ChinaChangshaChina 

出 版 物：《实用休克杂志（中英文）》 (Journal of Practical Shock)

年 卷 期：2023年第7卷第4期

页      面：250-256页

学科分类：100218[医学-急诊医学] 1002[医学-临床医学] 1010[医学-医学技术（可授医学、理学学位）] 10[医学] 

基　　金：Changsha Natural Science Foundation(NO.kq2208445) Changsha Central Hospital (NO.YNKY202306) Changsha Science and Technology Bureau(NO.kzd21084, kzd22074, kzd22075) 

主　　题：admitted patients sepsis 

摘      要：Objective Most patients with sepsis were diagnosed in the emergency department when admitted to the hospital. This study aimed to explore independent factors for hospital mortality in sepsis patients in the emergency *** It was a retrospective study. All patients with sepsis admitted to the emergency department of Changsha Central Hospital between 1 July 2020 and 1 July 2021 were included. Variables that showed significant differences between the survivor group and the non-survivor group were caculated in multivariate logistic regression analysis. Independent factors associated with in-hospital mortality in sepsis were *** A total of 194 patients were included in this study. In-hospital mortality was 17.01%(n=33). Two independent risk factors including albumin(ALB) and urea nitrogen were identified by multivariate logistic regression analysis. The optimal cut-off values of ALB and urea nitrogen were 26.5g/L and 8.03mmol/L. While combined ALB and urea nitrogen, the area under the ROC curve(AUC) was 0.790, which was superior to the SOFA, qSOFA, and APACHEⅡ*** Independent factors including ALB and urea nitrogen for in-hospital mortality in sepsis in the emergency department were identified. It could help physicians identify those patients with a higher risk of a poor prognosis early and easily, so intervention and management could be performed quickly.