Plasmonic nanostructures acting as a light-driven O_(2)-sensitive nitroreductase mimic for enhanced photochemical oxidation of para-aminothiophenol

作     者：Xinshuang Gao Jia-jia Zheng Hanbo Li Rui Cai Xingfa Gao Xiaochun Wu Xinshuang Gao;Jia-jia Zheng;Hanbo Li;Rui Cai;Xingfa Gao;Xiaochun Wu

作者机构：CAS Key Laboratory of Standardization and Measurement for NanotechnologyNational Center for Nanoscience and TechnologyBeijing 100190China Laboratory of Theoretical and Computational NanoscienceNational Center for Nanoscience and TechnologyBeijing 100190China University of Chinese Academy of SciencesBeijing 100049China 

出 版 物：《Nano Research》 (纳米研究（英文版）)

年 卷 期：2023年第16卷第11期

页      面：12697-12705页

核心收录：

学科分类：0710[理学-生物学] 081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 0805[工学-材料科学与工程（可授工学、理学学位）] 070303[理学-有机化学] 0703[理学-化学] 0702[理学-物理学] 

基　　金：supported by the National Key Basic Research Program of China(No.2021YFA1202803) the National Natural Science Foundation of China(No.22072032) the Strategic Priority Research Program of Chinese Academy of Sciences(No.XDB36000000) 

主　　题：plasmonic nanostructure nanozyme nitroreductase para-nitrothiolphenol hot electron injection para-aminothiolphenol 

摘      要：Nanozymes,as a novel form of enzyme mimics,have garnered considerable *** overcoming the main disadvantages of their natural analogs,they still face challenges such as restricted mimic types and low substrate ***,we introduce a reactive ligand modification strategy to diversify enzyme mimic ***,we have utilized helical plasmonic nanorods(HPNRs)modified with para-nitrothiophenol(4-NTP)to create an oxygen-sensitive nitroreductase(NTR)with *** act as a light-adjustable source of nicotinamide adenine dinucleotide/nicotinamide adenine dinucleotide phosphate(NAD(P)H),providing photon-generated energetic electrons to adsorbed 4-NTP *** the presence of O_(2),the activated 4-NTP transfers the captured electron to the adsorbed O_(2),mimicking the electron transfer process in its natural *** enhanced O_(2)activation notably boosts the oxidative coupling of para-aminothiophenol(4-ATP).Density functional theory(DFT)calculations reveal that hot electrons injected into the lowest unoccupied molecular orbital(LUMO)energy level of 4-NTP can be transferred to that of molecular *** conclusion,our findings underline the potential of the reactive ligand modification strategy in developing new types of enzyme reactions,which opens up promising avenues for the enhancement and diversification of nanozyme functionalities.