Helicobacter pylori eradication treatment for primary gastric diffuse large B-cell lymphoma:A single-center analysis
作者机构：Blood Disorders CenterAiiku HospitalSapporo 064-0804HokkaidoJapan Department of Cancer PathologyFaculty of MedicineHokkaido UniversitySapporo 060-8638HokkaidoJapan Department of Surgical PathologyHokkaido University HospitalSapporo 060-8648HokkaidoJapan
出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)
年 卷 期：2023年第11卷第27期
页 面：6424-6430页
核心收录：
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Primary gastric diffuse large B-cell lymphoma Treatment Helicobacter pylori Eradication
摘 要：BACKGROUND Unlike the already established effect of Helicobacter pylori(***)eradication on gastric mucosa-associated lymphoid tissue(MALT)lymphoma,its therapeutic effect on primary gastric diffuse large B-cell lymphoma(DLBCL)is still *** To clarify the efficacy of *** eradication treatment for primary gastric *** We reported on 3 new cases,and added them to 3 previously reported *** analyzed the usefulness of *** eradication treatment for gastric DLBCL for a total of 6 cases at our *** Of the 6 patients(27-90 years old,3 males and 3 females),all 3 patients with single lesions(one transformed from MALT lymphoma)achieved complete remission(CR)after *** *** the 2 newly reported cases,CR was maintained for more than 6 years with eradication treatment *** contrast,none of the 3 patients with 2 lesions achieved *** 1 newly reported case,endoscopic CR was achieved in one lesion,while stable disease was obtained in the other *** patients with progressive disease responded to standard chemo therapy±radiation and remained in CR for more than 6 *** We believe it is worthwhile to attempt *** eradication for elderly patients with primary gastric DLBCL in a single lesion with a small tumor burden.
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