Effects of obstructive sleep apnea on retinal microvasculature

作     者：Müjdat Karabulut Semai Bek Sinem Karabulut Aylin Karalezli Gülnihal Kutlu 

作者机构：Ophthalmology DepartmentMugla Sitki Kocman University Training and Research HospitalMugla 48300Türkiye Neurology DepartmentMugla Sitki Kocman University Faculty of MedicineMugla 48300Türkiye Ophthalmology DepartmentMugla Sitki Kocman University Faculty of MedicineMugla 48300Türkiye 

出 版 物：《国际眼科杂志:英文版》 (International Journal of Ophthalmology(English edition))

年 卷 期：2023年第16卷第10期

页      面：1670-1675页

核心收录：

学科分类：1002[医学-临床医学] 100212[医学-眼科学] 100213[医学-耳鼻咽喉科学] 10[医学] 

主　　题：apnoea-hypopnoea index deep capillary plexus obstructive sleep apnea superficial capillary plexus vessel density retinal microvasculature 

摘      要：AIM:To detect retinal microvascular variations in obstructive sleep apnea syndrome ***:This prospective,observational case-control study included healthy controls and patients with mild,moderate,and severe obstructive sleep apnea *** parameters,foveal avascular area,and flow areas in macula-centered,6.00×6.00 mm2 scan size optical coherence tomography angiography images were ***:The control group had the highest whole image,parafoveal,and perifoveal vessel density among the groups in both superficial and the deep capillary plexus(all P0.05).Rapid eye movement sleep apnoea-hypopnoea index was reversely correlated with whole(Rho=-0.195,P=0.034),parafoveal(Rho=-0.242,P=0.008),perifoveal(Rho=-0.187,P=0.045)vessel density in the superficial capillary plexus,and whole(Rho=-0.186,P=0.046),parafoveal(Rho=-0.260,P=0.004),perifoveal(Rho=-0.189,P=0.043)vessel density in the deep capillary plexus,though the mean and non-rapid eye movement sleep apnoeahypopnoea index related with only parafoveal vessel density in the superficial capillary plexus(Rho=-0.213,P=0.020;Rho=-0.191,P=0.038)and the deep capillary plexus(Rho=-0.254,P=0.005;Rho=-0.194,P=0.035).CONCLUSION:This study shows decreased vessel density and its reverse correlation with the apnoea-hypopnoea index in patients with obstructive sleep apnea syndrome.