Whole-genome sequencing in medicinal plants:current progress and prospect

作     者：Yifei Pei Liang Leng Wei Sun Baocai Liu Xue Feng Xiwen Li Shilin Chen 

作者机构：Institute of Chinese Materia MedicaChina Academy of Chinese Medical SciencesBeijing 100700China Institute of HerbgenomicsChengdu University of Traditional Chinese MedicineChengdu 611137China Innovative Institute of Chinese Medicine and PharmacyChengdu University of Traditional Chinese MedicineChengdu 611137China Institute of Agricultural BioresourceFujian Academy of Agricultural SciencesFuzhou 350003China 

出 版 物：《Science China(Life Sciences)》 (中国科学（生命科学英文版）)

年 卷 期：2024年第67卷第2期

页      面：258-273页

核心收录：

学科分类：0710[理学-生物学] 1008[医学-中药学(可授医学、理学学位)] 10[医学] 

基　　金：supported by Scientific and Technological Innovation Project of China Academy of Chinese Medical Sciences(CI2021A03910,CI2021A04106) the National Key Research and Development Program of China(2019YFC1710601) Fundamental Research Funds for the Central Public Welfare Research Institutes of China(ZXKT21026,ZZ15-YQ-033) Major Special Project of Scientific and Technological Cooperation of Bijie City(2021-02) 

主　　题：herbgenomics whole genome high throughput sequencing research strategy model species application 

摘      要：Advancements in genomics have dramatically accelerated the research on medicinal plants,and the development of herbgenomics has promoted the“Project of 1K Medicinal Plant Genometo decipher their genetic ***,it is difficult to obtain their high-quality whole genomes because of the prevalence of polyploidy and/or high genomic *** genomes of 123 medicinal plants were published until September *** published genome sequences were investigated in this review,covering their classification,research teams,ploidy,medicinal functions,and sequencing *** than 1,000 institutes or universities around the world and 50 countries are conducting research on medicinal plant *** species account for a majority of sequenced medicinal *** whole genomes of plants in the Poaceae family are the most *** 40%of the published papers studied species with tonifying,replenishing,and heat-cleaning medicinal *** plants are still in the process of domestication as compared with crops,thereby resulting in unclear genetic backgrounds and the lack of pure lines,thus making their genomes more difficult to *** addition,there is still no clear routine framework for a medicinal plant to obtain a high-quality whole ***,a clear and complete strategy has been originally proposed for creating a high-quality whole genome of medicinal ***,whole genome-based biological studies of medicinal plants,including breeding and biosynthesis,were *** also advocate that a research platform of model medicinal plants should be established to promote the genomics research of medicinal plants.