Integration and implementation of precision medicine in the multifaceted inflammatory bowel disease
作者机构：Department of MedicineSaint Francis Health Science CenterNewarkNJ 07107United States Department of MedicineSaint Francis Health SystemsTulsaOK 74133United States Department of ResearchColumbia UniversityNew YorkNY 10027United States Department of Medicine and PharmacologyTexas A&M UniversityCollege StationTX 77413United States
出 版 物：《世界胃肠病学杂志:英文版》 (World Journal of Gastroenterology)
年 卷 期：2023年第29卷第36期
页 面：5211-5225页
核心收录：
学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
主 题：Precision medicine Multiomics Inflammatory bowel disease Crohn’s disease Ulcerative colitis Data integration
摘 要：Inflammatory bowel disease(IBD)is a complex disease with variability in genetic,environmental,and lifestyle factors affecting disease presentation and *** medicine has the potential to play a crucial role in managing IBD by tailoring treatment plans based on the heterogeneity of clinical and temporal variability of *** medicine is a population-based approach to managing IBD by integrating environmental,genomic,epigenomic,transcriptomic,proteomic,and metabolomic *** is a recent and rapidly developing *** widespread adoption of precision medicine worldwide has the potential to result in the early detection of diseases,optimal utilization of healthcare resources,enhanced patient outcomes,and,ultimately,improved quality of life for individuals with *** precision medicine is promising in terms of better quality of patient care,inadequacies exist in the ongoing *** is discordance in study conduct,and data collection,utilization,interpretation,and *** review aims to describe the current literature on precision medicine,its multiomics approach,and future directions for its application in IBD.
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