Zinc and gastrointestinal disease

作     者：Sonja Skrovanek Katherine DiGuilio Robert Bailey William Huntington Ryan Urbas Barani Mayilvaganan Giancarlo Mercogliano James M Mullin 

作者机构：Lankenau Institute for Medical Research Lankenau Medical CenterWynnewood PA 19096 United States Division of Gastroenterology Lankenau Medical Center Wynnewood PA 19096 United States The Department of Medicine Lankenau Medical Center Wynnewood PA 19096 United States 

出 版 物：《World Journal of Gastrointestinal Pathophysiology》 (世界胃肠病理生理学杂志（英文版）（电子版）)

年 卷 期：2014年第5卷第4期

页      面：496-513页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Zinc Tight junction Nutrition Nutraceutical Micronutrient 

摘      要：This review is a current summary of the role that both zinc deficiency and zinc supplementation can play in the etiology and therapy of a wide range of gastrointestinal diseases. The recent literature describing zinc action on gastrointestinal epithelial tight junctions and epithelial barrier function is described. Zinc enhancement of gastrointestinal epithelial barrier function may figure prominently in its potential therapeutic action in several gastrointestinal diseases.