RBFOX2: a key factor in suppressing PDAC metastasis through regulation of alternative splicing events
作者机构：Department of GastroenterologyGastrointestinal Oncology and EndocrinologyUniversity Medical Center GottingenGottingenGermany Clinical Research Unit 5002KFO5002University Medical Center GöttingenGottingenGermany
出 版 物：《Signal Transduction and Targeted Therapy》 (信号转导与靶向治疗（英文）)
年 卷 期：2023年第8卷第10期
页 面：4431-4432页
核心收录：
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
基 金：funding enabled and organized by Projekt DEAL
主 题：metastasis al. metastatic
摘 要：A new study published in Nature by Jbara et *** identified the splicing factor“RBFOX2,which halts metastatic spread of pancreatic ductal adenocarcinoma(PDAC)through regulating alternative splicing events.1 The results of the study provide new insights into the molecular mechanisms underlying the start of metastatic spread of PDAC *** study also indicates that pathways involved in splicing modulation could be targeted for potential therapeutic interventions in an advanced-stage PDAC.
维普期刊数据库