Lacticaseibacillus rhamnosus Probio-M9 may be vertically transmitted from mother to infant during lactation based on faeces metagenomics

作     者：Lan Yang Lai-Yu Kwok Zhihong Sun Heping Zhang Lan Yang;Lai-Yu Kwok;Zhihong Sun;Heping Zhang

作者机构：Key Laboratory of Dairy Biotechnology and EngineeringMinistry of EducationInner Mongolia Agricultural UniversityHohhot 010018China Key Laboratory of Dairy Products ProcessingMinistry of Agriculture and Rural AffairsInner Mongolia Agricultural UniversityHohhot 010018China Inner Mongolia Key Laboratory of Dairy Biotechnology and EngineeringInner Mongolia Agricultural UniversityHohhot 010018China 

出 版 物：《Food Science and Human Wellness》 (食品科学与人类健康（英文）)

年 卷 期：2024年第13卷第2期

页      面：721-728页

核心收录：

学科分类：1002[医学-临床医学] 100211[医学-妇产科学] 10[医学] 

基　　金：supported by Science and Technology Major Projects of Inner Mongolia Autonomous Region(2021ZD0014) 

主　　题：Metagenomic analysis Lacticaseibacillus rhamnosus Gut microbiome Mother Infant 

摘      要：Probiotics exert beneficial effects on the *** study aimed to investigate whether maternally ingested Lacticaseibacillus rhamnosus Probio-M9 during pregnancy could access and colonize the infant *** study recruited one pregnant woman,who ingested Probio-M9 daily from 35 weeks of gestation to *** of the mother-infant pair were regularly collected from one month before delivery to 6 months of infant s age for metagenomic ***-M9 genomes were mappable to all infant fecal samples,suggesting the ingested probiotics could be vertically transmitted from mother to ***-or mother-specific differential metabolic pathways were found between the maternal and infant s gut microbiome,implicating apparent differences in the intestinal metagenomic potential/function between the mother and the *** conclusion,maternal ingestion of Probio-M9 during the final weeks of gestation could deliver to the infant *** findings provided novel insights into shaping infant s gut microbiota.