Pd-catalyzed cascade cyclization of allenylethylene carbonates and indandiones: Synthesis of tetracyclic dihydrocyclopentaindenofuranone derivatives

作     者：Yujie Dong Jun Liu Xing Gao Ting Pan Biming Mao Songcheng Yu Yongjun Wu Cheng Zhang Hongchao Guo Yujie Dong;Jun Liu;Xing Gao;Ting Pan;Biming Mao;Songcheng Yu;Yongjun Wu;Cheng Zhang;Hongchao Guo

作者机构：Department of Chemistry and Innovation Center of Pesticide ResearchChina Agricultural UniversityBeijing 100193China College of Public HealthZhengzhou UniversityZhengzhou 450001China 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2023年第34卷第10期

页      面：131-134页

核心收录：

学科分类：081702[工学-化学工艺] 08[工学] 0817[工学-化学工程与技术] 

基　　金：supported by the Natural Science Foundation of China(Nos.21871293 and 22071264) 

主　　题：Palladium Allenylethylene carbonates Indandiones Cascade cyclization Decarboxylation 

摘      要：A palladium-catalyzed cascade cyclization of allenylethylene carbonates with 1,3-indandiones was developed, providing biologically interesting tetracyclic dihydrocyclopentaindenofuranone derivatives having three contiguous quaternary carbon centers in moderate to high yields with excellent diastereoselectivities. In this reaction, the allene moiety was fully fused into the cyclopentene ring.