Dual-Emission Carbonized Polymer Dots Combined with Metal Ions as a Single-Component Fluorescence Sensor Array for Pattern Recognition of Glycosaminoglycans
作者机构:Jinhua PolytechnicJinhua 321000China Rizhao PolytechnicRizhao 276800China School of Chemistry and Molecular EngineeringShanghai Key Laboratory for Urban Ecological Processes and Eco-RestorationEast China Normal UniversityShanghai 200241China
出 版 物:《Journal of Analysis and Testing》 (分析检测(英文))
年 卷 期:2023年第7卷第3期
页 面:285-294页
核心收录:
学科分类:081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070302[理学-分析化学] 0703[理学-化学] 0714[理学-统计学(可授理学、经济学学位)] 0701[理学-数学]
基 金:supported by the National Natural Science Foundation of China(22274053) the Fundamental Research Funds for the Central Universities
主 题:CPDs GAGs Single-component Dual-emission Sensor array Biological fluids
摘 要:Herein,a novel dual-emission fluorescence sensor array of carbonized polymer dots(CPDs)-Cu^(2+)has been proposed,in which CPDs were prepared by one-pot hydrothermal method and Cu^(2+)acting as a quencher was combined with CPDs by electrostatic *** negatively charged glycosaminoglycans(GAGs)bearing different hydrophilic groups showed variable binding affinities towards CPDs-Cu^(2+).Upon reacting with these GAGs,the different fluorescence response signals of CPDs-Cu^(2+)can be further differentiated by principal component analysis(PCA).The CPDs-Cu^(2+)sensor array,not only allows the identification of four similarly structured GAGs,but also realizes the discrimination of different concentrations of the same GAGs and their ***,the identification of GAGs in biological fluids can also be achieved using our proposed single-component sensor array,validating its application *** new strategy avoids multiple sensing probes,broadens the application of tongue-mimic sensor arrays and provides a viable idea for the development of single component sensing platforms.