Dual-Emission Carbonized Polymer Dots Combined with Metal Ions as a Single-Component Fluorescence Sensor Array for Pattern Recognition of Glycosaminoglycans

作     者：Ziyang Lin Wenbang Yu Rong Hu Ruixuan Hu Zihan Wei Min Zhang 

作者机构：Jinhua PolytechnicJinhua 321000China Rizhao PolytechnicRizhao 276800China School of Chemistry and Molecular EngineeringShanghai Key Laboratory for Urban Ecological Processes and Eco-RestorationEast China Normal UniversityShanghai 200241China 

出 版 物：《Journal of Analysis and Testing》 (分析检测（英文）)

年 卷 期：2023年第7卷第3期

页      面：285-294页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070302[理学-分析化学] 0703[理学-化学] 0714[理学-统计学（可授理学、经济学学位）] 0701[理学-数学] 

基　　金：supported by the National Natural Science Foundation of China(22274053) the Fundamental Research Funds for the Central Universities 

主　　题：CPDs GAGs Single-component Dual-emission Sensor array Biological fluids 

摘      要：Herein,a novel dual-emission fluorescence sensor array of carbonized polymer dots(CPDs)-Cu^(2+)has been proposed,in which CPDs were prepared by one-pot hydrothermal method and Cu^(2+)acting as a quencher was combined with CPDs by electrostatic *** negatively charged glycosaminoglycans(GAGs)bearing different hydrophilic groups showed variable binding affinities towards CPDs-Cu^(2+).Upon reacting with these GAGs,the different fluorescence response signals of CPDs-Cu^(2+)can be further differentiated by principal component analysis(PCA).The CPDs-Cu^(2+)sensor array,not only allows the identification of four similarly structured GAGs,but also realizes the discrimination of different concentrations of the same GAGs and their ***,the identification of GAGs in biological fluids can also be achieved using our proposed single-component sensor array,validating its application *** new strategy avoids multiple sensing probes,broadens the application of tongue-mimic sensor arrays and provides a viable idea for the development of single component sensing platforms.