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Studies on plasma-activated perilla seed oil:Diagnosis,optimisation,and validation of reactive species

作     者:Xiaolong Wang Jun Liu Quanxin Li Lian Li Shanrui Li Yunhan Ding Tong Zhao Ying Sun Yuantao Zhang Xiaolong Wang;Jun Liu;Quanxin Li;Lian Li;Shanrui Li;Yunhan Ding;Tong Zhao;Ying Sun;Yuantao Zhang

作者机构:School of Electrical EngineeringShandong UniversityJinanChina State Grid Hubei Electric Power Co.Ltd.WuhanChina The Second Hospital of Shandong UniversityShandong UniversityJinanChina Key Laboratory of Chemical Biology(Ministry of Education)Institute of Biochemical and Biotechnological DrugsSchool of Pharmaceutical SciencesCheeloo College of MedicineShandong UniversityJinanChina 

出 版 物:《High Voltage》 (高电压(英文))

年 卷 期:2023年第8卷第4期

页      面:841-851页

核心收录:

学科分类:0710[理学-生物学] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 07[理学] 070204[理学-等离子体物理] 0703[理学-化学] 0702[理学-物理学] 

基  金:National Natural Science Foundation of China,Grant/Award Number:52077128 Fundamental Research Funds for the Central Universities,Grant/Award Number:2022JC027 Natural Science Foundation of Shandong Province,Grant/Award Number:ZR2020ME208 

主  题:reactive cancer radical 

摘      要:Recently,the applications of cold atmospheric plasma(CAP)in liquid treatment have attracted increasing attention owing to its excellent medical *** has been proved that CAP can effectively enhance the biological activity of vegetable oils due to the generation of reactive *** the reactor parameter is an important approach to regulate reactive species in plasma-activated oil to obtain better biological *** this study,a self-made jet array driven by a pulsed power supply was used to generate large-area plasma to irradiate perilla seed oil(PSO),with the formation of plasmaactivated perilla seed oil(PAPSO).By means of laser-induced fluorescence and chemical titration,the relative density of hydroxyl radical radical in plasma jet,as well as the activity of PAPSO were measured under different discharge parameters,and realised the control of the activity of *** vitro experiments showed that PAPSO significantly enhanced its ability to inhibit cancer cells proliferation and induce apoptosis after plasma treatment,which provides a reference for cancer *** study is helpful to further understand the influence of plasma dose effect on the activity of media and provide guidance for related plasma medical applications.

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