Global and national burden of atherosclerosis from 1990 to 2019:trend analysis based on the Global Burden of Disease Study 2019

作     者：Weihua Chen Zeya Li Yu Zhao Yitian Chen Rongchong Huang 

作者机构：Department of CardiologyBeijing Friendship HospitalCapital Medical UniversityBeijing 100053China Department of CardiologyLongyan First Affiliated Hospital of Fujian Medical UniversityLongyanFujian 364000China 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2023年第136卷第20期

页      面：2442-2450页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：supported by grants from the Summit Talent Plan Beijing Hospital Management Center(No.DFL20190101 Beijing China) 

主　　题：Atherosclerosis Disability-adjusted life years(DALYs) Global Disease Burden 2019 Incidence Mortality 

摘      要：Background:Atherosclerosis-related diseases represent significant health issues among adults *** their widespread impact,comprehensive data concerning the global and national burden and trends of these diseases remain *** objective is to examine the trends in the burden of atherosclerosis among adults from 1990 to 2019 at both global and national ***:We reported the average annual percentage changes(AAPCs)in prevalence,incidence,mortality,and disabilityadjusted life years(DALYs)of atherosclerosis-related diseases(ischemic heart disease[IHD],ischemic stroke,and peripheral arterial disease[PAD])at the global and national levels among individuals based on a trend analysis of the Global Burden of Diseases Study(GBD)*** further analyzed these global trends as a function of age,gender,and the social development *** also used joinpoint regression analysis to identify the year with the most substantial changes in global ***:Globally,the AAPC of IHD incidence rose from 1990 to 2019(0.20;95%confidence interval[CI],0.12-0.28),with substantial surges in 1995,2001,2005,2010,and ***,AAPC of IHD mortality rates exhibited a different trend until a rise in *** AAPC of incidence rates of ischemic stroke and PAD also escalated during the same period,with respective 0.43(95%CI,0.39-0.48)and 0.13(95%CI,0.06-0.21).For ischemic stroke,both incidence and mortality soared in 2014,while PAD incidence declined in 1994 and 1998,then sharply climbed in ***,the Northern Mariana Islands experienced the steepest increase in IHD and PAD incidence and mortality between 1990 and *** saw a significant rise in ischemic stroke incidence,whereas the highest mortality rate increase occurred in *** sociodemographic index(SDI)quintile,low-middle-,middle-,and high-middle-SDI countries all showed upward trends in IHD,ischemic stroke,and PAD ***,IHD and ischemic stroke mortality rates,as well