Analysis of the Effect of Hormone Therapy Combined with Hydroxychloroquine in the Treatment of IgA Nephropathy

作     者：Guolin Liu 

作者机构：Jiuquan HospitalJiayuguan 735100Gansu ProvinceChina 

出 版 物：《Journal of Clinical and Nursing Research》 (临床护理研究（英文）)

年 卷 期：2023年第7卷第4期

页      面：185-190页

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

主　　题：Hormone therapy Hydroxychloroquine IgA nephropathy 

摘      要：Objective:To explore and analyze the effect of hormone therapy combined with hydroxychloroquine in the treatment of IgA ***:30 patients with IgA nephropathy who were admitted to the Urology Department of Jiuquan hospital from August 2021 to May 2023 were selected as the research subjects,and they divided into an observation group and control group by drawing lots,with 15 cases in each *** observation group underwent hydroxychloroquine treatment in addition of hormone therapy,and the control group underwent conventional treatment and hormone *** rate of effectiveness of treatment,serum index,and renal function of both groups were ***:The incidence of adverse reactions in the observation group was significantly lower than that in the control group(P0.05)between the groups before treatment;after treatment,the serum creatinine and serum albumin in the steroid group were significantly better than those in the reference group(P0.05);after treatment,the hormone group’s urine protein quantification and glomerular filtration rate were significantly better than those in the reference group(P0.05).The rate of effectiveness of the hormone group was significantly higher than that of the reference group(P0.05).Conclusion:Hormone therapy combined with hydroxychloroquine in the treatment of IgA nephropathy is more effective than hormone therapy alone,thus this treatment plan is worthy of promotion and application.