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Prognosis related genes in HER2+ breast cancer based on weighted gene co-expression network analysis

Prognosis related genes in HER2+ breast cancer based on weighted gene co-expression network analysis

作     者:Yujie Weng Rong Jia Zhongxian Li Wei Liang Yucheng Ji Ying Liang Pengfei Ning 

作者机构:College of Computer and InformationInner Mongolia Medical UniversityHohhotInner Mongolia Autonomous Region 010110China 

出 版 物:《Chinese Medical Journal》 (中华医学杂志(英文版))

年 卷 期:2023年第136卷第10期

页      面:1258-1260页

核心收录:

学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主  题:breast HER2 Breast 

摘      要:To the Editor:Breast cancer is one of the malignant diseases that cause death in women and is a severe threat to women’s health.With the progress of medical treatment,there are many methods to treat breast cancer,such as drug therapy and hormone therapy.Among them,molecular targeted therapy has dramatically improved the treatment effect of breast cancer.Therefore,it is vital to find important molecular markers.[1]Breast cancer can be divided into four subtypes:triple-negative(TN),lumA,lumB,and HER2+.[2]HER2+breast cancer accounts for 15–20%of breast cancers,with a higher grade,a more aggressive phenotype,and a worse prognosis.

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