Synthesis and Lubrication of Phosphorylcholine Derivative

作     者：Zhenliang Qiao~1, Dangsheng Xiong~1, Lude Lu~2, Pengju Jiang~2 1. Department of Materials Science and Engineering, Nanjing University of Science and Technology, Nanjing 210094, P.R. China 2. School of Chemical Engineering, Nanjing University of Science and Technology, Nanjing 210094, P. R. China 

作者机构：Department of Materials Science and Engineering Nanjing University of Science and Technology Nanjing P.R. China School of Chemical Engineering Nanjing University of Science and Technology Nanjing P. R. China 

出 版 物：《Journal of Bionic Engineering》 (仿生工程学报（英文版）)

年 卷 期：2010年第7卷第3期

页      面：254-258页

核心收录：

学科分类：081702[工学-化学工艺] 08[工学] 0817[工学-化学工程与技术] 

基　　金：the National Natural Science Foundation of China(50975145) the High Technology Project of Jiangsu Province(BC20077046)for their financial support 

主　　题：artificial joint articular cartilage molecular lubrication mechanism phosphorylcholine synthesis UHMWPE 

摘      要：The monomer of phosphorylcholine derivative, O-(5-（2-methacryloxy）-3, 3-dimethyl-3-azapentyl)-O’-（ω-hydroxy-octyl）-phosphatequaternary ammonium salt, was designed and synthesized successfully. It was characterized by the spectra ofHNMR and Mass spectra （ESI+）, and every signal was assigned. Then the lubricating characteristics of the phosphorylcholinederivative were investigated on the tribological setup of ball-oh-flat. The Ultra-High Molecular Weight Polyethylene（UHMWPE） flat was rotated against a stainless steel ball with 6 mm diameter. The load was 2.3 N, which corresponded to amaximal Hertz contact pressure of 29 MPa. Water, phosphorylcholine derivative, and Acrylic Acid （AA） solution were used aslubricants, respectively. Compared with AA, the phosphorylcholine derivative shows significant lubrication. It can be stronglyhydrated under water due to the charged segment in chemical structure. The thick water layers within the chains serves asboundary lubricants, and this is thought to be the molecular origins of lubricating behavior.