COVID-19-induced gastrointestinal autonomic dysfunction:A systematic review

作     者：Reem Elbeltagi Mohammed Al-Beltagi Nermin Kamal Saeed Adel Salah Bediwy 

作者机构：Department of MedicineThe Royal College of Surgeons in Ireland-Medical University of BahrainBusiateen 15503MuharraqBahrain Department of PaediatricsFaculty of MedicineTanta UniversityTanta 31511AlgharbiaEgypt Department of PaediatricsUniversity Medical CenterArabian Gulf UniversityManama 26671ManamaBahrain Department of PaediatricsUniversity Medical CenterKing Abdulla Medical CityArabian Gulf UniversityDr Sulaiman Al Habib Medical GroupManama 26671ManamaBahrain Medical Microbiology SectionPathology DepartmentSalmaniya Medical ComplexMinistry of HealthKingdom of BahrainManama 12ManamaBahrain Microbiology SectionPathology DepartmentThe Royal College of Surgeons in Ireland-Medical University of BahrainBusaiteen 15503MuharraqBahrain Department of Chest DiseaseFaculty of MedicineTanta UniversityTanta 31527AlgharbiaEgypt Department of PulmonologyUniversity Medical CenterKing Abdulla Medical CityArabian Gulf UniversityDr Sulaiman Al Habib Medical GroupManama 26671ManamaBahrain 

出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)

年 卷 期：2023年第11卷第22期

页      面：5252-5272页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：COVID-19 SARS-CoV-2 Gastrointestinal autonomic dysfunction Long COVID Post-COVID Autonomic nervous system 

摘      要：BACKGROUND It is common for severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection to occur in the gastrointestinal tract,which can present itself as an initial *** severity of coronavirus disease 2019(COVID-19)is often reflected in the prevalence of gastrointestinal ***-19 can damage the nerve supply to the digestive system,leading to gastrointestinal autonomic *** is still much to learn about how COVID-19 affects the autonomic nervous system and the gastrointestinal *** To thoroughly explore the epidemiology and clinical aspects of COVID-19-induced gastrointestinal autonomic dysfunction,including its manifestations,potential mechanisms,diagnosis,differential diagnosis,impact on quality of life,prognosis,and management and prevention *** We conducted a thorough systematic search across various databases and performed an extensive literature *** review encompassed 113 studies published in English from January 2000 to April 18,*** According to most of the literature,gastrointestinal autonomic dysfunction can seriously affect a patient s quality of life and ultimate *** factors can influence gastrointestinal autonomic nervous *** have shown that SARS-CoV-2 has a well-documented affinity for both neural and gastrointestinal tissues,and the virus can produce various gastrointestinal symptoms by reaching neural tissues through different *** symptoms include anorexia,dysgeusia,heartburn,belching,chest pain,regurgitation,vomiting,epigastric burn,diarrhea,abdominal pain,bloating,irregular bowel movements,and *** is the most prevalent symptom,followed by anorexia,nausea,vomiting,and abdominal *** COVID-19 vaccination may rarely induce autonomic dysfunction and gastrointestinal symptoms,COVID-19-induced autonomic effects significantly impact the patient s condition,general health,prognosis,and quality of *** diagnosis a