Synthesis and characterization of a new biodegradable polyurethanes with good mechanical properties

作     者：Wen-Qiang Qu Yi-Ran Xia Li-Juan Jiang Li-Wei Zhang Zhao-Sheng Hou 

作者机构：College of Chemistry Chemical Engineering and Materials ScienceCollaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong Shandong Normal University Shandong Academy of Pharmaceutical Sciences Shandong Provincial Key Laboratory of Biomedical Polymer Shandong Success Pharmaceutical Technology Co. Ltd. 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2016年第27卷第1期

页      面：135-138页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070305[理学-高分子化学与物理] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 0703[理学-化学] 

基　　金：financially supported by Shandong Provincial Natural Science Foundation, China (No. ZR2013EMM004) Jinan City Universities and Institutes Independent Innovation Planning Project, China (No. 201402044) 

主　　题：Ring-opening polymerization Biodegradable Polyurethanes Mechanical property 

摘      要：In the paper, a new biodegradable polyurethane（PU, PU-I） was prepared： the prepolymer was synthesized via bulk ring-opening polymerization with poly（ethylene glycol）（M_n= 600）（PEG600） as an initiator and L-lactide（L-LA）, e-caprolactone（CL） as monomers, and the prepolymer was chain-extended with an isocyanate-terminated urethane triblock（macrodiisocyanate） to prepare the PU. The macrodiisocyanate, prepolymer and PUs were characterized by^1H NMR,^（13）C NMR, FT-IR, high resolution mass spectrometry（HR-MS）, gel permeation chromatography（GPC）, thermo gravimetric analysis（TGA）,and differential scanning calorimetry（DSC）. The corresponding PU films showed excellent mechanical properties with a tensile strength of 27.5 MPa and an elongation at break of 996%, and also maintained mechanical properties in physiological saline at 37℃ for more than three weeks, which appeared to be more suitable for biomedical applications.