From amides to urea derivatives or carbamates with chemospecific C–C bond cleavage at room temperature

作     者：Cong Lv Dan Liu Tegshi Muschin Chaolumen Bai Agula Bao Yong-Sheng Bao 

作者机构：College of Chemistry and Environmental ScienceInner Mongolia Key Laboratory of Green catalysisInner Mongolia Normal UniversityHohhot010022China 

出 版 物：《Organic Chemistry Frontiers》 (有机化学前沿（英文）)

年 卷 期：2022年第9卷第5期

页      面：1354-1363页

核心收录：

学科分类：0710[理学-生物学] 1002[医学-临床医学] 07[理学] 1001[医学-基础医学(可授医学、理学学位)] 0828[工学-农业工程] 0903[农学-农业资源与环境] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：Financial support from the National Nature Science Foundation of China(21861030) the Inner Mongolia Nature Science Foundation(2021MS02030) the Special Founded Project for Cultivating Major Project of Inner Mongolia Normal University(2020ZD02) the Innovative and Entrepreneurial Startup Supporting Program of Returned Overseas Scholars of Inner Mongolia Autonomous Region,the Collaborative Innovation Center for Water Environmental Security of Inner Mongolia Autonomous Region(XTCX003) the Science and Technology Program of Inner Mongolia Autonomous Region(2020PT0003)is acknowledged. 

主　　题：temperature cleavage bond 

摘      要：Ureas and carbamates are common motifs in pharmaceuticals,agrochemicals,biologically active com-pounds and organocatalysis applications.Herein,we report a significant advancement in this area and present a general method for copper-catalyzed chemospecific C–C bond cleavage of amides to syn-thesize urea derivatives and carbamates at room temperature.