Antioxidant,hypolipidemic and hypoglycemic effect of red wine in wistar rats fed with obesogenic diet

作     者：Cornélio Mucaca José Henrique Tavares Filho Luciana Lima Arruda André Martins Galvão Maria Bernadete de Sousa Maia Eryka Maria dos Santos Alves Eryvelton de Souza Franco Elizabeth do Nascimento 

作者机构：Department of NutritionCenter of Health SciencesFederal University of Pernambuco (UFPE)Cidade Universitaria50670-901RecifePEBrazil Rural Technology DepartmentFederal Rural University of Pernambuco (UFRPE)AD.Manoel de Medeiros Ave.s/nDois Irmãos52171-900RecifePEBrazil Department of Physiology and PharmacologyCenter of Biological SciencesFederal University of Pernambuco (UFPE)Cidade Universitaria50670-901RecifePEBrazil 

出 版 物：《Food Bioscience》 (食品生物科学（英文）)

年 卷 期：2022年第47卷第3期

页      面：756-764页

核心收录：

学科分类：0832[工学-食品科学与工程（可授工学、农学学位）] 1006[医学-中西医结合] 10[医学] 100602[医学-中西医结合临床] 

主　　题：Dyslipidemia Obesity Rats Westernized diet Red wine 

摘      要：The health benefits resulting from the usual ingestion of red wines have been studied in humans and animals.However,the evaluation of benefits in antioxidant,hypoglycemic and hypolipemic activity concomitant with the use of an obesogenic diet in adult Wistar rats has been little explored.The present study investigated the use of red wine derived from Northeast Brazil in adult rats fed with an obesogenic diet on antioxidant activity,glucose tolerance,adipose,glycemic and lipemic profile.Sixty 45-day old male Wistar rats formed two groups:standard diet and westernized diet.After changes in body mass and glycemic levels,the animals were subdivided into six subgroups (n = 10 per group) and received water,red wine or hydroalcoholic solution by gavage.The data reveal that the moderate and chronic use of red wine improves the glycemic,lipid and oxidative stress profile,being favorable in preventing the risk of cardiovascular diseases in rats fed with an obesogenic diet.