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Should gastroenterologists prescribe cannabis? The highs, the lows and the unknowns

作     者:Sonia Samuel Mark Michael Micheal Tadros 

作者机构:Department of Internal MedicineAlbany Medical CenterAlbanyNY 12208United States Department of Gastroenterology and HepatologyAlbany Medical CenterAlbanyNY 12208United States 

出 版 物:《World Journal of Clinical Cases》 (世界临床病例杂志)

年 卷 期:2023年第11卷第18期

页      面:4210-4230页

核心收录:

学科分类:1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 1002[医学-临床医学] 100602[医学-中西医结合临床] 10[医学] 

主  题:Marijuana cannabis Endocannabinoid system Side effects Gastrointestinal disorders 

摘      要:Cannabis,commonly known as marijuana,is a drug extracted from the Cannabis plant known for its psychotropic and medicinal *** has been used for healing purposes during ancient times,although its psychoactive components led to its restricted use in ***,cannabis is found to have modulatory effects on the endocannabinoid system exhibiting its medicinal role in the gastrointestinal(GI)*** animal and human studies demonstrate the influential effects of cannabis on a variety of GI diseases including inflammatory bowel disease,motility disorders and GI *** also has a regulatory role in GI symptoms including nausea and vomiting,anorexia,weight gain,abdominal pain,among ***,both its acute and chronic use can lead to undesirable side effects such as dependency and addiction,cognitive impairment and cannabinoid hyperemesis *** will discuss the role of cannabis in the GI system as well as dosing strategies to help guide gastroenterologists to assess its efficacy and provide patient counseling before prescription of medical marijuana.

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