Mechanism and effects of extramedullary hematopoiesis on anti-tumor immunity

作     者：Zefang Chen Xinyu Cheng Li Yang Xiaoming Cheng Bo Zhu Haixia Long Zefang Chen;Xinyu Cheng;Li Yang;Xiaoming Cheng;Bo Zhu;Haixia Long

作者机构：Institute of CancerXinqiao HospitalThird Military Medical UniversityChongqing 400037China School of Pharmacy and BioengineeringChongqing University of TechnologyChongqing 400054China Department of Respiratory DiseaseXinqiao HospitalThird Military Medical UniversityChongqing 400037China 

出 版 物：《Cancer Biology & Medicine》 (癌症生物学与医学（英文版）)

年 卷 期：2023年第20卷第7期

页      面：477-482页

核心收录：

学科分类：1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 100214[医学-肿瘤学] 10[医学] 

基　　金：supported by grants from the National Natural Science Foundation of China(Grant No.82150119 to HX.L.and Grant No.8223000771 to B.Z.) 

主　　题：immunity immunotherapy Cancer 

摘      要：Cancer immunotherapy is a preferred strategy for boosting anti-tumor immunity to eliminate malignant cells and is considered a major breakthrough in the field of cancer treatment however,immunosuppressive cells in the tumor microenvironment(TME)pose a major obstacle to the efficacy of *** cells,such as tumor-a ssociated macrophages(TAMs)and myeloid-derived suppressor cells(MDSCs).