CK5/6-positive,P63-positive lymphoepithelioma-like hepatocellular carcinoma:A case report and literature review
作者机构:Graduate School of Guangdong Medical UniversityZhanjiang 524002Guangdong ProvinceChina Department of Hepatobiliary SurgeryZhongshan People’s HospitalZhongshan 528400Guangdong ProvinceChina
出 版 物:《World Journal of Clinical Cases》 (世界临床病例杂志)
年 卷 期:2023年第11卷第19期
页 面:4640-4647页
核心收录:
学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
基 金:Supported by Zhongshan Bureau of Science and Technology,No.2017B1044 and No.2017SYF04
主 题:Liver cancer Lymphoepithelioma-like carcinoma Hepatocellular carcinoma Epstein–Barr virus Literature review Case report
摘 要:BACKGROUND Lymphoepithelioma-like carcinoma(LELC),a rare and unique variant of liver cancer,can be divided into lymphoepithelioma-like hepatocellular carcinoma and lymphoepithelioma-like intrahepatic *** lymphocytic infiltration is its characteristic pathological *** recent years,the number of reported cases of this type has increased each *** have shown that lymphoepithelioma-like cholangiocarcinoma occurs more frequently in Asian women;LELC is associated with Epstein–Barr virus infection of liver cells of epithelial *** research shows that the prognosis of this tumour is *** SUMMARY A 38-year-old female patient was hospitalized after 3 mo of abdominal pain and *** had been infected with hepatitis B virus more than 10 years *** patient was hospitalized on January 21,*** resonance imaging showed a 36 mm×28 mm mass under the envelope of the left inner lobe of the *** metastasis of lymph nodes or other organs was *** left hemihepatectomy,biopsy and immunohistochemistry yielded a final diagnosis of lymphoepithelial hepatocellular *** 12 mo of outpatient follow-up and chemotherapy,no tumour metastases were found on the latest computed tomography *** Herein,the patient was treated surgically and then followed up as an outpatient for 12 *** case will further expand our overall knowledge of the diagnosis and treatment of this rare tumor.