Effect of ginger on gastric motility and symptoms of functional dyspepsia
Effect of ginger Effect of ginger on gastric motility and symptoms of functional dyspepsiaon gastric motility and symptoms of functional dyspepsia作者机构：Division of Hepatogastroenterology Department of Internal Medicine Chang Gung Memorial Hospital- Kaohsiung Medical Center Chang Gung University College of Medicine Kaohsiung 83301 Taiwan Discipline of Medicine University ofAdelaide Royal Adelaide Hospital Adelaide SA 5000 Australia
出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)
年 卷 期：2011年第17卷第1期
页 面：105-110页
核心收录：
学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
基 金：Supported by Grant from National Research Program from National Science Council (NMRP870071)
主 题：Ginger(Zinger offinale) Functional dyspepsia Gastric emptying Antral contraction Abdominal ultrasound Ghrelin Glucagon-like peptide-1 Motilin
摘 要：AIM:To evaluate the effects of ginger on gastric motility and emptying,abdominal symptoms,and hormones that influence motility in ***:Eleven patients with functional dyspepsia were studied twice in a randomized double-blind *** an 8-h fast,the patients ingested three capsules that contained ginger(total 1.2 g) or placebo,followed after 1 h by 500 mL low-nutrient *** area,fundus area and diameter,and the frequency of antral contractions were measured using ultrasound at frequent intervals,and the gastric half-emptying time was calculated from the change in antral *** sensations and appetite were scored using visual analog questionnaires,and blood was taken for measurement of plasma glucagon-like peptide-1(GLP-1),motilin and ghrelin concentrations,at intervals throughout the ***:Gastric emptying was more rapid after ginger than placebo [median(range) half-emptying time 12.3(8.5-17.0) min after ginger,16.1(8.3-22.6) min after placebo,P ≤ 0.05].There was a trend for more antral contractions(P = 0.06),but fundus dimensions and gastrointestinal symptoms did not differ,nor did serum concentrations of GLP-1,motilin and ***:Ginger stimulated gastric emptying and antral contractions in patients with functional dyspepsia,but had no impact on gastrointestinal symptoms or gut peptides.
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