Effect of Traditional Chinese Medicine combined with Western Medicine on blood lipid levels and inflammatory factors in patients with angina pectoris in coronary heart disease identified as intermingled phlegm and blood stasis syndrome:a network Meta-anal

作     者：WANG Chao WU Qiong LI Ping WANG Zhigang LOU Xusheng LI Yuanyuan ZHANG Lin WANG Chao;WU Qiong;LI Ping;WANG Zhigang;LOU Xusheng;LI Yuanyuan;ZHANG Lin

作者机构：Postdoctoral Mobile Station of Chinese Academy of Traditional Chinese medicineBeijing 100700China China Academy of Chinese Medical SciencesBeijing 100700China Zang-xiang Teaching and Research Departmentthe Institute of Basic Theory for Chinese MedicineChina Academy of Chinese Medical SciencesBeijing 100700China Department of Cardiovascular Medicine Beijing University of Chinese Medicine Third Affiliated HospitalBeijing 100029China Shandong College of Traditional Chinese MedicineYantai 264199China School of Traditional Chinese MedicineBeijing University of Chinese MedicineBeijing 102488China 

出 版 物：《Journal of Traditional Chinese Medicine》 (中医杂志（英文版）)

年 卷 期：2023年第43卷第4期

页      面：640-649页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：the Fundamental Research Funds for the Central Public Welfare Research Institutes:Theoretical Study of Combination of Facial Color and Pulses Mode in Traditional Chinese Medicine(No.KJ-202013) Objective Study of“Wei Qi”in Pulse Based on Color Doppler Flow Imaging(CDFI)Technology(No.YZ-202124) 

主　　题：coronary disease angina pectoris phlegm and blood stasis interaction blood lipid inflammatory factors medicine traditional Chinese network Meta-analysis randomized controlled trial 

摘      要：OBJECTIVE:To evaluate the clinical efficacy of Traditional Chinese Medicine prescriptions for resolving phlegm in the treatment of angina pectoris of phlegmstasis coronary heart disease by a network ***:Randomized controlled trials(RCTs)on clinical efficacy of CHD angina pectoris with interaction of phlegm and blood stasis were searched in PubMed,Springer,the Cochrane Library and Chinese-language databases China National Knowledge Infrastructure,China Science and Technology Journal Database,and Wanfang Data from their inception to December *** was screened and literature bias risk was assessed by RevMan5.4 *** overall response rate,the duration of angina attack,the levels of serum lipids such as total cholesterol(TC),triglyceride(TG),low density lipoprotein cholesterol(LDL-C),and high density lipoprotein cholesterol(HDL-C),and expression of hypersensitive C-reactive protein(hs-CRP)were selected as outcome indicators for network Meta-analysis and mapped using Stata15.1 ***:Totally,26 RCTs were included,involving 2098 *** were 6 TCM formulas with the effects of dispelling phlegm and removing blood *** conventional Western Medicine as the common intervention measures,the results showed that the overall response improvement rate from high to low was displayed as modified Xiaoxianxiong decoction(小陷胸汤,MXD),Danlou tablet(丹蒌片,DT),modified Gualou Xiebai Banxia decoction(瓜蒌薤白半夏汤,MGXBD),modified Wendan decoction(温胆汤,MWD),modified Zhishi Xiebai Guizhi decoction(枳实薤白桂枝汤,MZXGD),and modified Erchen decoction(二陈汤,MED).The sequence of angina attack duration improvement from high to low was MZXGD,MGXBD,DT,MWD,*** sequence of TC improvement from high to low was MZXGD,MED,DT,and *** of improving TG from high to low was MED,MZXGD,MGXBD,and *** LDL-C improvement,the effect from good to poor was MZXGD,MGXBD,DT,and *** regard to HDL-C improvement,the effect was ranked as MED,MZXGD,MGXBD,and