Outcomes of vitrectomy,complete pan-retinal photocoagulation,and endoscopic cyclophotocoagulation surgery after anti-VEGF treatment in neovascular glaucoma

作     者：Jinglan Li Siwenyue Zhang Baoke Hou 

作者机构：Medical School of Chinese PLABeijingChina Senior Department of OphthalmologyThe Third Medical Center of PLA General HospitalBeijingChina 

出 版 物：《Advances in Ophthalmology Practice and Research》 (眼科实践与研究新进展(英文))

年 卷 期：2023年第3卷第3期

页      面：112-118页

学科分类：1002[医学-临床医学] 100212[医学-眼科学] 10[医学] 

基　　金：supported by the Clinical diagnosis and treatment technology and translational application in Beijing (Z211100002921049) 

主　　题：Neovascular glaucoma Endoscopic cyclophotocoagulation Pars plana vitrectomy Pan-retinal photocoagulation Anti-VEGF 

摘      要：Purpose:To establish a comprehensive treatment strategy and evaluate the efficacy of combination of anti-vascular endothelial growth factor(VEGF)injection,pars plana vitrectomy(PPV),endoscopic pan-retinal photocoagulation(PRP),and endoscopic cyclophotocoagulation(ECP)surgery for neovascular glaucoma(NVG)***:This retrospective study included 30 patients(30 eyes)who were suffering from NVG and treated with PPV&PRP&ECP(ECP group,16 eyes),or Ahmed glaucoma valve implantation(Ahmed group,14 eyes).The intraocular pressure(IOP),number of postoperative anti-glaucoma medications,best-corrected visual acuity(BCVA),successful rate of surgery,and postoperative complications were recorded and statistically analyzed at the time points of preoperative,1-day,1-month,3-months,6-months,and 12-months after ***:An obvious reduction in IOP and number of postoperative anti-glaucoma medications were observed in both the ECP group and Ahmed group after operation(P0.05),while it was significantly improved in ECP group at 3-months(P=0.001),6-months(P=0.004),and 12-months(P=0.010)time points comparing with preoperative *** surgical success rates in ECP group were also slightly higher than Ahmed *** the complications after operation showed no marked ***:The comprehensive treatment of PPV,endoscopic PRP,and ECP surgery for NVG patients after antiVEGF injection can control IOP effectively and be friendly to patients’BCVA without obvious serious complications throughout a 12-months follow-up period.