Targeting host-microbe interaction in mucus layer:a potential treatment option for diseases

作     者：Hyun Ho Choi Mong-Hong Lee 

作者机构：Guangdong Research Institute of GastroenterologyThe Sixth Affiliated Hospital of Sun Yat-Sen UniversityGuangzhouGuangdongP.R.China 

出 版 物：《Gastroenterology Report》 (胃肠病学报道（英文）)

年 卷 期：2019年第7卷第1期

页      面：1-2,I0001页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：intestine 疾病治疗 黏液层 

摘      要：Human gut microbiota,containing at least 100 trillion bacteria,resides in the mucosal surface of the human *** individual is host to a distinct set of at least 160 species in the *** collective microbial genome encodes 500 times more genes than the human genome,and so it is tempting to consider human genes as noise in the storm of microbial signals[1].Recent data suggest that,while microbial signals modulate crucial functions of the healthy human body,there are also accumulating data suggesting that many human diseases have their origin in distorted gut microbiota composition[2].