Impact of anastomotic leakage on long-term prognosis after colorectal cancer surgery

作     者：Valeria Tonini Manuel Zanni 

作者机构：Department of Medical and Surgical SciencesUniversity of BolognaBologna 40138BolognaItaly 

出 版 物：《World Journal of Gastrointestinal Surgery》 (世界胃肠外科杂志（英文版）（电子版）)

年 卷 期：2023年第15卷第5期

页      面：745-756页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Anastomotic leakage Colorectal surgery Colon cancer Rectal cancer Long term prognosis Long term survival 

摘      要：Colorectal cancer(CRC)is one of the most common malignancies in the *** significant improvements in surgical technique,postoperative complications still occur in a fair percentage of patients undergoing colorectal *** most feared complication is anastomotic *** negatively affects shortterm prognosis,with increased post-operative morbidity and mortality,higher hospitalization time and ***,it may require further surgery with the creation of a permanent or temporary *** there is no doubt about the negative impact of anastomotic dehiscence on the short-term prognosis of patients operated on for CRC,still under discussion is its impact on the long-term *** authors have described an association between leakage and reduced overall survival,disease-free survival,and increased recurrence,while other Authors have found no real impact of dehiscence on long term *** purpose of this paper is to review all the literature about the impact of anastomotic dehiscence on long-term prognosis after CRC *** main risk factors of leakage and early detection markers are also summarized.