You had me at PELO:a"Ribosome Rescuer"induces NLR inflammasome assembly

作     者：Zoie Magri Alexander Poltorak 

作者机构：Graduate Program in ImmunologyTufts Graduate School of Biomedical Sciences136 Harrison AvenueBostonMA02111USA Department of ImmunologyTufts University School of MedicineBostonMA02111USA 

出 版 物：《Cellular & Molecular Immunology》 (中国免疫学杂志（英文版）)

年 卷 期：2024年第21卷第1期

页      面：1-2页

核心收录：

学科分类：1001[医学-基础医学(可授医学、理学学位)] 100104[医学-病理学与病理生理学] 10[医学] 

主　　题：inflam NLR distress 

摘      要：Pyroptosis,an inflammatory form of programmed cell death,eliminates a niche where pathogens replicate,providing overall benefits to a *** left uncontrolled,pyroptosis can lead to severe *** pyroptotic activation has been implicated in neuroinflammation,cardiovascular disease,acute respiratory distress syndrome(ARDS),and many other diseases[1,2,3].Because of its multiple and permanent consequences,pyroptosis is a highly regulated signaling *** regulators of pyroptosis are NLR inflammasomes,which are activated by various“dangersignals such as ATP.