Electrophysiology as a tool to unravel the origin of pancreatic pain
作者机构：Mech-SenseDepartment of Gastroenterology of HepatologyM?lleparkvej 4Aalborg University Hospital Division of NeurologyOspedale Pediatrico Bambino GesùIRCCS Department of Health Science and TechnologyCenter for Sensory-Motor InteractionsAalborg University
出 版 物：《World Journal of Gastrointestinal Pathophysiology》 (世界胃肠病理生理学杂志（英文版）（电子版）)
年 卷 期：2014年第5卷第1期
页 面：33-39页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Chronic pancreatitis Electrophysiology Evoked potentials Brain source localization Electroencephalography frequency analysis Visceral pain Chronic pain Pancreatic pain
摘 要：Intense abdominal pain is the most common symptom in chronic pancreatitis, but the underlying mechanisms are not completely understood and pain management remains a significant clinical *** focus of pain origin in chronic pancreatitis traditionally has been on the pancreatic gland, assuming pain to originate in the pancreas or its surrounding organs. However, research in the last decade points to abnormal central nervous system pain *** this reason, electroencephalography has been receiving increasing attention. In contrast to imaging methods such as functional magnetic resonance and positron emission tomography, electroencephalogram has excellent temporal resolution making it possible to investigate central processing of pain on a millisecond time scale. Moreover, continuously advancing methodology made it possible to explore brain sources responsible for generation of evoked potentialsand hence to study brain reorganization due to pain in chronic pancreatitis. The aim of this review is to give an overview of the current methods and findings in electroencephalography as a tool to unravel the origin of pancreatic pain.
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