The Potential Impact of EIF4E3 and LARP1 on Tumor Immunity in Hepatocellular Carcinoma
作者机构:Shenzhen Traditional Chinese Medicine Hospital Affiliated to Nanjing University of Chinese MedicineShenzhen 518033GuangdongChina Department of Liver DiseaseShenzhen Traditional Chinese Medicine HospitalShenzhen 518033GuangdongChina
出 版 物:《Biomedical and Environmental Sciences》 (生物医学与环境科学(英文版))
年 卷 期:2023年第36卷第5期
页 面:469-475页
核心收录:
学科分类:0830[工学-环境科学与工程(可授工学、理学、农学学位)] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题:Carcinoma diagnosis treatment
摘 要:Hepatocellular carcinoma(HCC) is a highly aggressive primary liver malignancy and the third most common cause of cancer-related deaths worldwide. Although early HCC can be treated through surgical resection, liver transplantation, and radical ablation, the early recurrence rate after treatment is 70%[1]. Systemic therapy, such as molecular-targeted agents, has made great advances in HCC treatment, but the optimal therapeutic approaches are still limited due to insidious onset and late diagnosis[2]. Therefore, efficient HCC treatment strategies should be developed urgently.