The Association between Vitamin D and Hashimoto Thyroiditis:An Upto-date Systematic Review and Meta-analysis

作     者：Zhengrong Liu Linfei Feng Yanfang He Sijie Yuan Chao Xu 

作者机构：The Out Patient DepartmentNanfang HospitalSouthern Medical UniversityGuangzhou 510515China Psychology DepartmentNanfang HospitalSouthern Medical UniversityGuangzhou 510515China The Department of General PracticeNanfang HospitalSouthern Medical UniversityGuangzhou 510515China Office of The Standardized Residents Training in HospitalsGraduate SchoolSouthern Medical UniversityGuangzhou 510515China 

出 版 物：《Food Materials Research》 (食材研究（英文）)

年 卷 期：2022年第2卷第1期

页      面：82-91页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：25(OH)D_(3) vitamin insufficiency 

摘      要：The objective of the surrent study was to summarize the up-to-date studies to investigate the relationship between vitamin D and Hashimoto thyroiditis(HT).An online search of English and Chinese databases was *** studies concerned the investigation of the relationship between vitamin D and HT including meta-analysis,meanwhile the heterogeneities were revealed by subgroup *** six elated studies containing 15,336 participants(HT:6,138 versus control:9,198)were *** patients had lower levels of 25(OH)D_(3)(standardised mean difference,−1.09;95%CI:[−1.42,−0.75];P0.01),and were more likely to be deficient in 25(OH)D_(3)(OR,2.77;95%CI,[1.88,3.91];P0.05).Obvious heterogeneities in the results of meta-analysis were down to the difference of detection methods and criteria of vitamin D insufficiency among *** D deficiency was colncluded to have a significant relation with HT.