Cross-Frequency Coupling and Intelligent Neuromodulation

作     者：Chien-Hung Yeh Chuting Zhang Wenbin Shi Men-Tzung Lo Gerd Tinkhauser Ashwini Oswal 

作者机构：School of Information and ElectronicsBeijing Institute of TechnologyBeijingChina Department of Biomedical Sciences and EngineeringNational Central UniversityTaoyuanTaiwan Department of NeurologyBern University Hospital and University of BernBernSwitzerland MRC Brain Network Dynamics UnitUniversity of OxfordOxfordUK 

出 版 物：《Cyborg and Bionic Systems》 (类生命系统（英文）)

年 卷 期：2023年第4卷第1期

页      面：284-297页

核心收录：

学科分类：12[管理学] 1201[管理学-管理科学与工程(可授管理学、工学学位)] 081104[工学-模式识别与智能系统] 08[工学] 0835[工学-软件工程] 0811[工学-控制科学与工程] 0812[工学-计算机科学与技术（可授工学、理学学位）] 

基　　金：supported by the National Natural Science Foundation of China(Nos.62171028 and 62001026) the BIT National High-level Fellow Research Fund Pro gram(No.3050012222022) the MRC Clinician Scientist Fellowship(No.MR/W024810/1) the Swiss National Science Foundation(No.PZ00P3_202166) the National Science and Technology Council(Nos.110-2221-E-008-093,111-2221-E-008-015-MY3,111-2221-E008-103-MY3,and 111-2218-E-008-009) 

主　　题：epilepsy spite evident 

摘      要：Cross-frequency coupling(CFC)reflects(nonlinear)interactions between signals of different *** from both patient and healthy participant studies suggests that CFC plays an essential role in neuronal computation,interregional interaction,and disease *** present review discusses methodological advances and challenges in the computation of CFC with particular emphasis on potential solutions to spurious coupling,inferring intrinsic rhythms in a targeted frequency band,and causal *** specifically focus on the literature exploring CFC in the context of cognition/memory tasks,sleep,and neurological disorders,such as Alzheimer s disease,epilepsy,and Parkinson s ***,we highlight the implication of CFC in the context and for the optimization of invasive and noninvasive neuromodulation and ***,CFC could support advancing the understanding of the neurophysiology of cognition and motor control,serve as a biomarker for disease symptoms,and leverage the optimization of therapeutic interventions,e.g.,closed-loop brain *** the evident advantages of CFC as an investigative and translational tool in neuroscience,further methodological improvements are required to facilitate practical and correct use in cyborg and bionic systems in the field.