Phototheranostic Nanoagents for Imaging-Guided Treatment of Oral Cancer
作者机构：Central Laboratory of Tianjin Stomatological HospitalTianjin Key Laboratory of Oral and Maxillofacial Function ReconstructionTianjin Stomatological HospitalThe Affiliated Stomatological Hospital of Nankai UniversityTianjin300041 China Key Laboratory of Bioactive MaterialsMinistry of Educationand College of Life SciencesNankai UniversityTianjin300071 China
出 版 物：《中国化学:英文版》 (Chinese Journal of Chemistry)
年 卷 期：2023年第41卷第13期
页 面：1624-1636页
核心收录：
学科分类：1002[医学-临床医学] 07[理学] 070205[理学-凝聚态物理] 08[工学] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 0703[理学-化学] 100214[医学-肿瘤学] 0702[理学-物理学] 10[医学]
基 金：supported by the National Key R&D Program of China(Intergovernmental Cooperation Project,2017YFE0132200) the National Natural Science Foundation of China(82101032) the Science and Technology Project of Tianjin Health Commission(TJWJ2021MS039) the Fundamental Research Funds for the Central Universities(63223030) the Tianjin Key Medical Discipline(Specialty)Construction Project(No.TJYXZDXK-078D)
主 题：Phototheranostic Nanoagents Sensors Bioimaging Oral cancer Cancer treatment
摘 要：Phototherapy showed almost a lack of drug resistance and,depending on the therapeutic effects of non-invasive light-stimulating *** side effects of phototherapy were greatly reduced compared to their traditional *** nanoagents had new properties in drug delivery,biocompatibility,targeting and response,in which traditional phototheranostic drugs can not ***,a large number of relevant studies have demonstrated that photodynamic therapy(PDT)in combination with other agents and image-guided multifunctional photothermal therapy(PTT)were well suited for the treatment of oral *** the design of the nanoagents,researchers have discovered various applications for phototherapy,such as targeted release of co-packaged drugs,multifunctional imaging for diagnosis and treatment combination,accurate targeting caused by nanocarriers,and synergistic chemotherapy with *** this paper,we first reviewed the research related to phototheranostic nanoagents for image-guided treatment of oral *** tried to introduce the design concept and the treatment effect by three parts of components of phototheranostic nanoagents,categories of phototheranostic nanoagents and application of phototheranostic *** also provided a reference for nanomaterial development and clinical applications in research of oral cancer treatment.
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