Visible Light-Induced C-5 Selective C-H Radical Borylation of Imidazo[1,2-a]pyridines with NHC-Boranes

作     者：Huitao Zheng Hao Lu Chaobo Su Runlong Yang Limin Zhao Xiang Liu Hua Cao Huitao Zheng;Hao Lu;Chaobo Su;Runlong Yang;Limin Zhao;Xiang Liu;Hua Cao

作者机构：School of Chemistry and Chemical Engineering and Guangdong Cosmetics Engineering&Technology Research CenterGuangdong Pharmaceutical UniversityZhongshanGuangdong 528458China 

出 版 物：《Chinese Journal of Chemistry》 (中国化学（英文版）)

年 卷 期：2023年第41卷第2期

页      面：193-198页

核心收录：

学科分类：07[理学] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：This work was supported by the Innovation and Strong School Project of Guangdong Pharmaceutical University(2021ZDzX2028) the Scientific and Technological Innovation Leading Talent Project of Zhongshan City(LJ2021009) a Start-up Grant from Guangdong Pharmaceutical University(Grant Nos.51361303,51361304). 

主　　题：Photochemistry Boron C-H activation Imidazo[12-a]pyridines Radicals Synthetic methods 

摘      要：A visible-light-induced C-5 selective C-H borylation of imidazo[1,2-a]pyridines with NHC-BH3 via Minisci-type radical borylation re-action has been developed for the first time.The present sustainable protocol provides a new family of regioselectively C5-borylated imidazopyridines that would otherwise be difficult to prepare.It is a supplement to site-selective borylation of azines(nitrogen-con-taining aromatic heterocycles)and the assembly of sp2 carbon-boron bond.