Assessing the effectiveness of quarantine measures during the COVID-19 pandemic in Chile using Bayesian structural time series models
作者机构：Nursing SchoolFaculty of Health and Social SciencesUniversidad de las AméricasConcepciònChile Faculty of NursingUniversidad de ConcepciònConcepciònChile Department of StatisticsUniversidad de ConcepciònConcepciònChile Applied Mathematics Group(GMA)Faculty of SciencesUniversidad del BiobíoConcepciònChile Nursing SchoolFaculty of Health and Social SciencesUniversidad de las AméricasSantiagoChile
出 版 物：《Infectious Disease Modelling》 (传染病建模（英文）)
年 卷 期：2022年第7卷第4期
页 面：625-636页
学科分类：0710[理学-生物学] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 100401[医学-流行病与卫生统计学] 10[医学]
主 题：Comovement Bayesian time series models Novel coronavirus 2010 MSC 00e01 99-00
摘 要：Background:With the emergence of the COVID-19 pandemic,all existing health protocols were tested under the worst health crisis humanity has experienced since the Black Death in the 14th century.Countries in Latin America have been the epicenter of the COVID-19 pandemic,with more than 1.5 million people killed.Worldwide health measures have included quarantines,border closures,social distancing,and mask use,among others.In particular,Chile implemented total or partial quarantine measures depending on the number of infections in each region of the country.Therefore,it is necessary to study the effectiveness of these quarantines in relation to the public health measures implemented by government entities at the national level.Objective:The main objective of this study is to analyze the effectiveness of national-and region-level quarantines in Chile during the pandemic based on information published by the Chilean Ministry of Health,and answers to the following question are sought:Were quarantine measures in Chile effective during the COVID-19 pandemic?Methods:The causal effect between the rates of COVID-19 infections and the population rates in Phase 1 and Phase 2 quarantines in the period from March 2020 to March 2021 in different regions of Chile were evaluated using intervention analyses obtained through Bayesian structural time series models.In addition,the Kendall correlation coefficient obtained through the copula approach was used to evaluate the comovement between these rates.Results:In 75%of the Chilean regions under study(12 regions out of a total of 16),an effective Phase 1 quarantine,which was implemented to control and reduce the number of cases of COVID-19 infection,was observed.The main regions that experienced a decrease in cases were those located in the north and center of Chile.Regarding Phase 2,the COVID-19 pandemic was effectively managed in 31%(5 out of 16)of the regions.In the southcentral and extreme southern regions of Chile,the effectiveness of these phases was null.Conclusion:The findings indicate that in the northern and central regions of Chile,the Phase 1 quarantine application period was an effective strategy to prevent an increase in COVID-19 infections.The same observation was made with respect to Phase 2,which was effective in five regions of northern Chile;in the rest of the regions,the effectiveness of these phases was weak or null.
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