CD74:a prospective marker for reactive microglia?

作     者：Phani Sankar Potru Björn Spittau Phani Sankar Potru;Bj?rn Spittau

作者机构：Anatomy and Cell BiologyMedical School OWLBielefeld UniversityBielefeldGermany(Potru PS)Faculty of BiologyBielefeld UniversityBielefeldGermany 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2023年第18卷第12期

页      面：2673-2674页

核心收录：

学科分类：0710[理学-生物学] 07[理学] 1001[医学-基础医学(可授医学、理学学位)] 071006[理学-神经生物学] 

主　　题：CD74 prospective MHCⅡ 

摘      要：Cluster of differentiation 74(CD74),also called as major histocompatibility complex class Ⅱ(MHCⅡ)invariant chain,is involved in trafficking MHCⅡ cell surface molecules on antigen-presenting cells and has been implicated in many signaling pathways.For example,the interaction between CD74 and macrophage migration inhibitory factor cyto kine(MIF) leads to the activation of a plethora of pathways such as extracellular regulated protein kinases,phosphoinositide 3-kinase.