Pichia as yeast cell factory for production of industrially important bio-products:Current trends,challenges,and future prospects
作者机构：Department of BiosciencesManipal University JaipurJaipur 303007India Sardar Swaran Singh National Institute of Bio-EnergyJalandhar 144601India
出 版 物：《Journal of Bioresources and Bioproducts》 (生物质资源与工程（英文）)
年 卷 期：2023年第8卷第2期
页 面：108-124页
核心收录：
学科分类：0202[经济学-应用经济学] 02[经济学] 020205[经济学-产业经济学]
主 题：Natural product Pichia Non-conventional yeast Biosynthesis System biology Synthetic biology
摘 要：Yeast has been used as a cell factory for thousands of years to produce a wide variety of com-plex biofuels,bioproducts,biochemicals,food ingredients,and *** a variety of biotechnological production hosts,a few specific genera of yeast have proven *** developments in metabolic engineering and synthetic biology provide a workable long-term supply solution for these *** this review,we have covered recent advances in the design of yeast cell factories for the synthesis of terpenoids,alkaloids,phenylpropanoids,and other natural chemicals,primarily focusing on Pichia ***-edge solutions involving genetic and process engineering have also been ***,the review summarized recent advancements and challenges in synthetic and systems biology,as well as initiatives in metabolic engineering aimed at commercializing non-conventional yeasts like *** processes used in non-traditional yeasts to produce enzymes,therapeutic proteins,lipids,and metabolic products for industrial applications were thoroughly elaborated.
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