Prevalence, Risk Factors, and Awareness of Chronic Kidney Disease among Diabetes Mellitus and Hypertensive Individuals at the Buea Regional Hospital, Cameroon

作     者：Patience Nformi Ndapkwi Elisabeth Zeuko’o Menkem Oteh Njockawoh Mpey Eleonore Ngounou Woquan Sama Luma Watching Djakissam Erastus Nembo Nembu Jackson Seukep Armel Francis Désiré Bomba Taksinkou Denis Teuwafeu Fabrice Fekam Boyom Patience Nformi Ndapkwi;Elisabeth Zeuko’o Menkem;Oteh Njockawoh Mpey;Eleonore Ngounou;Woquan Sama Luma;Watching Djakissam;Erastus Nembo Nembu;Jackson Seukep Armel;Francis Désiré Bomba Taksinkou;Denis Teuwafeu;Fabrice Fekam Boyom

作者机构：Department of Biomedical Sciences Faculty of Health Sciences University of Buea Buea Cameroon Antimicrobial and Biocontrol Agent Unit Laboratory for Phytobiochemistry and Medicinal Plants Studies Department of Biochemistry Faculty of Sciences University of Yaoundé 1 Yaoundé Cameroon Department of Medical Laboratory Sciences Faculty of Health Sciences University of Buea Buea Cameroon Department of Internal Medicine and Pediatrics Faculty of Health Sciences University of Buea Buea Cameroon 

出 版 物：《Journal of Biosciences and Medicines》 (生物科学与医学（英文）)

年 卷 期：2023年第11卷第4期

页      面：260-277页

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

主　　题：Chronic Kidney Disease Prevalence Risk Factors Hypertension Diabetes Mellitus 

摘      要：Background: Kidney failure, cardiovascular disease, and early mortality are just a few of the major negative effects of chronic renal disease, a serious global health issue. The considerable financial and public health burden associated with chronic kidney disease can be lessened by raising awareness and adopting better practices for its impact, prevention, and early identification. Objective: In this study, individuals with hypertension and diabetes were evaluated for their knowledge of chronic kidney disease, its prevalence, and its risk factors. Method: It was a hospital-based cross-sectional study conducted on adult (18 years) patients with diabetes mellitus and hypertension. Each participant provided written informed consent before having their data collected through interviews, medical information, and blood samples for CKD screening. The CKD epidemiology collaboration (CKD-EPI) equation was used to calculate the glomerular filtration rate (GFR) from serum creatinine, and CKD was determined using the estimated GFR (e-GFR). To find independent CKD factors, multivariate logistic regression was employed, with a p-value of 0.05 being regarded as statistically significant. This was accomplished using SPSS (Statistical Program for Social Sciences) version 22.0, IBM Corp., Armonk, NY. Result: A total of 156 participants took part in the study among which 95 (60.9%) were male, most of the participants 82 (52.6%) were aged between 51 - 70 years (mean 59.42 ± 11.007), 76 (48.7%) were unemployed and 97 (62.2%) were single. Overall, the knowledge score of participants on CKD was 65.4% for good knowledge and 34.6% for poor or inadequate knowledge of CKD. More than half of the participants (60%) had chronic kidney disease. Among these, the greatest proportion of CKD patients were those who were hypertensive (88.2%) followed by those who were both hypertensive and diabetic (70.7%). Conclusion: There is poor management of CKD in the South West Region of Cameroon which has co