An overview of functional biolubricants

作     者：Lumin YANG Xiaoduo ZHAO Zhengfeng MA Shuanhong MA Feng ZHOU Lumin YANG;Xiaoduo ZHAO;Zhengfeng MA;Shuanhong MA;Feng ZHOU

作者机构：State Key Laboratory of Solid LubricationLanzhou Institute of Chemical PhysicsChinese Academy of SciencesLanzhou 730000China Center of Materials Science and Optoelectronics EngineringUniversity of Chinese Academy of SciencesBeijing 100049China Yantai Zhongke Research Institute of Advanced Materials and Green Chemical EngineeringYantai 264006China Shandong Laboratory of Yantai Advanced Materials and Green ManufactureYantai 264006China 

出 版 物：《Friction》 (摩擦（英文版）)

年 卷 期：2023年第11卷第1期

页      面：23-47页

核心收录：

学科分类：0710[理学-生物学] 08[工学] 080203[工学-机械设计及理论] 0802[工学-机械工程] 

基　　金：We are grateful for the financial support from the National Natural Science Foundation of China(22032006 and 52075522) Key Research Project of Shandong Provincial Natural Science Foundation(ZR2021ZD27) Outstanding Youth Fund of Gansu Province(21JR7RA095) LICP Cooperation Foundation for Young Scholars(HZJ21-04). 

主　　题：biolubricants eye drops tissue anti-adhesion arthritis treatment medical devices 

摘      要：At present,more and more diseases are associated with the lubrication dysfunction,which requires a systematic study of the complex lubrication behavior of tissues and organs in human body.Natural biomacromolecular lubricants are essential for maintaining ultra-low coefficients of friction between sliding biological interfaces.However,when the surface lubrication performance of tissues or organs destroys heavily,it will bring friction/shear damage for sliding contact interfaces.Therefore,the application of exogenous biological lubricating materials to improve the lubrication situation of damaged tissue or organ interfaces has attracted extensive attention of researchers.In this review,based on a simple summary of lubrication mechanism at sliding biological interface,we systematically introduce the research progress of several kinds of representatively biolubrication materials,including eye drops,tissue anti-adhesion agents,joint lubricants,and medical device lubricants.Meanwhile,the lubrication mechanism and individual advantage and shortcoming for each of these synthetic exogenous lubricated materials are clarified.Correspondingly,the important lubrication application functionality of these biolubricant materials in typically medical surgery scenes,such as dry eye syndrome,tissue adhesion,arthritis,and interventional medical devices,is discussed.Finally,we look forward to the future development direction of artificial biolubricant materials.