Correlation between the Six-Minute Walk Test and Subjective Functional Class in Patients with Heart Failure

作     者：Davi Muzi Rios Gabriela Lira Devens Leticia Admiral Louzada Priscila Cabral Gomes Coelho Lima Rodolfo Costa Sylvestre Vinicius Angelo Astolpho Lucas Crespo de Barros Larissa Novaes Paganini Lucas Martins Frizzera Borges Renato Giestas Serpa Osmar Araujo Calil Luiz Fernando Machado Barbosa Roberto Ramos Barbosa Davi Muzi Rios;Gabriela Lira Devens;Leticia Admiral Louzada;Priscila Cabral Gomes Coelho Lima;Rodolfo Costa Sylvestre;Vinicius Angelo Astolpho;Lucas Crespo de Barros;Larissa Novaes Paganini;Lucas Martins Frizzera Borges;Renato Giestas Serpa;Osmar Araujo Calil;Luiz Fernando Machado Barbosa;Roberto Ramos Barbosa

作者机构：Department of Cardiology Santa Casa de Misericórdia de Vitória Hospital Vitória Brazil School of Medicine Santa Casa de Misericórdia Vitória Brazil 

出 版 物：《World Journal of Cardiovascular Diseases》 (心血管病（英文）)

年 卷 期：2023年第13卷第4期

页      面：205-213页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Heart Failure Six-Minute Walk Test Functional Class 

摘      要：Introduction: The Six-Minute Walk Test (6MWT) is an inexpensive method to objectively evaluate physical capacity or limitation and stratify prognosis in patients with Heart Failure (HF). Since the clinical perception of symptoms may be adapted or compromised, regular evaluation from medical interviews often fails to determine functional classification. This study aimed to assess the correlation between New York Heart Association Functional Class (NYHA-FC) and the distance walked in the 6MWT. Methods: We conducted a cross-sectional observational study that included patients with HF with reduced ejection fraction followed up at an outpatient service of a teaching hospital, from August 2018 to April 2019. Patients in NYHA-FC I, II, or III were included. We compared NYHA-FC subjectively obtained during the consultation with the 6MWT performed after medical consultation, and the correlation between these two parameters was assessed. Results: The study included 70 patients with HF, 41 (58.6%) of whom were female. The mean age was 61.2 ± 12.7 years. The most prevalent etiologies were dilated idiopathic cardiomyopathy (35.7%) followed by ischemic cardiomyopathy (25.7%). The mean ejection fraction was 34.1% ± 9.8%. The average distance walked in the 6MWT by NYHA-FC I patients was 437.8 ± 95.8 meters, NYHA-FC II 360.1 ± 96.4, and NYHA-FC III 248.4 ± 98.3. Functional class measured by the 6MWT was different than that estimated by NYHA-FC in 34 patients (48.6%), 23 (32.9%) for a higher functional class and 11 (15.7%) for a lower one (p = 0.07). Pearson’s correlation coefficient between NYHA-FC and the 6MWT was -0.55. Conclusion: There was a moderate correlation between the subjective NYHA-FC and the 6MWT. The 6MWT revealed a different classification from NYHA-FC in almost half of the patients. Among those who presented discrepancies between methods, 6MWT reclassification towards a higher functional class was more common.