Trisubstituted alkenes featuring aryl groups:stereoselective synthetic strategies and applications

作     者：Meng-Yao Li Shuyang Zhai Xiao-Mei Nong Ao Gu Jiatong Li Guo-Qiang Lin Yingbin Liu Meng-Yao Li;Shuyang Zhai;Xiao-Mei Nong;Ao Gu;Jiatong Li;Guo-Qiang Lin;Yingbin Liu

作者机构：Shanghai Cancer InstituteRenji Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200127China Shanghai Institute of Organic ChemistryChinese Academy of SciencesShanghai 200032China School of Basic Medicine and Clinical PharmacyChina Pharmaceutical UniversityNanjing 211198China 

出 版 物：《Science China Chemistry》 (中国科学（化学英文版）)

年 卷 期：2023年第66卷第5期

页      面：1261-1287页

核心收录：

学科分类：081702[工学-化学工艺] 08[工学] 0817[工学-化学工程与技术] 

基　　金：supported by the National Natural Science Foundation of China(81874181,21871284) the Major Scientific and Technological Special Project for“Significant New Drugs Creation”(2019ZX09301158) the Emerging Frontier Program of Hospital Development Centre(SHDC12018107) the Science&Technology Department of Shanghai(18401933500) the State Key Laboratory of Bioorganic and Natural Products Chemistry 

主　　题：trisubstituted alkenes stereoselective synthesis aggregation-induced emission transition metal catalysis 

摘      要：In recent years,the synthesis and application of alkenes have attracted increased ***(TriPEs)have lower molecular torsion than tetraphenylethenes(TPEs),which helps to balance the degree of conjugation and the aggregation-induced emission(AIE)*** geometry of double bonds has a significant impact on ***,it is essential to provide a comprehensive summary of the stereoselective synthetic strategies for trisubstituted *** this review,common strategies for the stereoselective synthesis of alkenes are described,with an emphasis on the origin of stereoselectivity and the types of *** addition,the AIE properties of TriPE and its applications in optoelectronic devices,stimuli-responsive materials,sensors,and therapies were discussed.