Properties and applications of embryonic stem cells

作     者：GUO Xiaoxia & HE Fuchu1. Beijing Institute of Radiation Medicine, Beijing 100850, China 2. Department of Life Science, Shandong University, Ji’nan 250100, China Correspondence should he addressed to He Fuchu 

作者机构：Beijing Institute of Radiation Medicine Beijing China Department of Life Science Shandong University Ji’nan China 

出 版 物：《Chinese Science Bulletin》 (CHINESE SCIENCE BULLETIN)

年 卷 期：2000年第45卷第14期

页      面：1258-1265页

核心收录：

学科分类：08[工学] 09[农学] 0901[农学-作物学] 0836[工学-生物工程] 090102[农学-作物遗传育种] 

基　　金：G1999053903 39990660 

主　　题：embryonic stem cell differentiation in vitro cell transplantation therapy gene targeting. 

摘      要：Mouse embryonic stem (ES) cells are pluripotent cells derived from the early embryo and can be propagated stably in undifferentiated state in vitro. They retain the ability to differentiate into all cell types found in the embryonic and adult body in vivo, and can be induced to differentiate into many cell types under appropriate culture conditions in vitro. Using these properties, people have set up various differentiated systems of many cell types and tissues in vitro. Through analysis of these systems, one can identify novel bioactive factors and reveal mechanisms of cell differentiation and organogenesis. ES cell-derived differentiated cells can also be applied to cell transplantation therapy. In addition, we summarized the features and potential applications of human ES cells.