Current trends in perioperative treatment of resectable gastric cancer

作     者：İbrahim Yıldız Leyla Özer Elif Şenocak Taşçı İbrahim Vedat Bayoglu Erman Aytac 

作者机构：Department of Medical OncologyAcıbadem MAA Universityİstanbul 34567Turkey Department of Medical OncologyAcıbadem Universityİstanbul 34567Turkey Department of Medical OncologyMarmara Universityİstanbul 12345Turkey Department of SurgeryAcibadem University School of MedicineIstanbul 34567Turkey 

出 版 物：《World Journal of Gastrointestinal Surgery》 (世界胃肠外科杂志（英文版）（电子版）)

年 卷 期：2023年第15卷第3期

页      面：323-337页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Perioperative treatment Immunotherapy Neoadjuvant Chemotherapy Gastric cancer Adjuvant 

摘      要：In the last few decades,the treatment strategy for locally advanced resectable gastric cancer(GC)has shifted to a multimodal approach,which potentially decreases recurrence risk and improves survival *** therapy leads to downstaging,increased curative resection rates,and prolonged disease-free and overall survival,by preventing micrometastases in patients with resectable *** of neoadjuvant therapy provides information about tumor biology and in vivo sensitivity.A consensus regarding the therapeutic approach for non-metastatic GC does not exist,and many clinical trials aim to clarify this *** in precision medicine and the role of immunotherapy have been the focus of research in GC ***,the current status and possible future developments of perioperative therapy for locally advanced resectable GC are reviewed,based on the most recent randomized clinical trials.