Endoscopic mucosal resection with double band ligation versus endoscopic submucosal dissection for small rectal neuroendocrine tumors

作     者：Jia-Lan Huang Ri-Yun Gan Ze-Han Chen Ruo-Yu Gao De-Feng Li Li-Sheng Wang Jun Yao 

作者机构：Department of GastroenterologyThe Second Clinical Medical CollegeJinan UniversityShenzhen 518020Guangdong ProvinceChina Department of GastroenterologyShenzhen Luohu People's HospitalShenzhen 518020Guangdong ProvinceChina Department of GastroenterologyShenzhen People's Hospital(The Second Clinical Medical CollegeJinan University/The First Affiliated HospitalSouthern University of Science and Technology)Shenzhen 518020Guangdong ProvinceChina 

出 版 物：《World Journal of Gastrointestinal Surgery》 (世界胃肠外科杂志（英文版）（电子版）)

年 卷 期：2023年第15卷第3期

页      面：440-449页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：Supported by Technical Research and Development Project of Shenzhen No.JCYJ20210324113215040 

主　　题：Small rectal neuroendocrine tumor Endoscopic submucosal dissection Endoscopic mucosal resection Ligation complete resection rate Complication 

摘      要：BACKGROUND Endoscopic resection remains an effective method for the treatment of small rectal neuroendocrine tumors(NETs)(≤10 mm).Moreover,endoscopic mucosal resection(EMR)with double band ligation(EMR-dB),a simplified modification of EMR with band ligation,is an alternative strategy to remove small rectal *** To evaluate the feasibility and safety of EMR-dB for the treatment of small rectal NETs(≤10 mm).METHODS A total of 50 patients with small rectal NETs,without regional lymph node enlargement or distant metastasis confirmed by endoscopic ultrasound,computerized tomography scan,or magnetic resonance imaging,were enrolled in the study from March 2021 to June *** patients were randomly assigned into the EMR-dB(n=25)group or endoscopic submucosal dissection(ESD)group(n=25).The characteristics of the patients and tumors,procedure time,devices cost,complete resection rate,complications,and recurrence outcomes were *** There were 25 patients(13 males,12 females;age range 28-68 years old)in the EMR-dB group,and the ESD group contained 25 patients(15 males,10 females;age range 25-70 years old).Both groups had similar lesion sizes(EMR-dB 4.53±1.02 mm,ESD 5.140±1.74 mm;P=0.141)and resected lesion sizes(1.32±0.52 cm vs 1.58±0.84 cm;P=0.269).Furthermore,the histological complete resection and en bloc resection rates were achieved in all patients(100%for each).In addition,there was no significant difference in the complication rate between the two ***,the procedure time was significantly shorter and the devices cost was significantly lower in the EMRdB ***,there was no recurrence in both groups during the follow-up *** The procedure time of EMR-dB was shorter compared with ESD,and both approaches showed a similar curative *** together,EMR-dB was a feasible and safe option for the treatment of small rectal NETs.