Role of T-box transcription factor 3 in gastric cancers

作     者：Naoki Asano Akira Imatani Akio Takeuchi Masashi Saito Xiao-Yi Jin Waku Hatta Kaname Uno Tomoyuki Koike Atsushi Masamune 

作者机构：Division of GastroenterologyTohoku University Graduate School of MedicineSendai 980-8574Japan 

出 版 物：《World Journal of Gastrointestinal Pathophysiology》 (世界胃肠病理生理学杂志（英文版）（电子版）)

年 卷 期：2023年第14卷第2期

页      面：12-20页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：Supported by Grants-in-Aid for Scientific Research from the Japanese Society for the Promotion of Science No.18K07928 No.19K08411 and No.22K08025 

主　　题：Aging Wnt β-catenin Transforming growth factor-β Stomach Carcinogenesis 

摘      要：The expression of T-box transcription factor 3(TBX3)has been identified in various cancers,including gastric *** role in breast cancers and melanomas has been intensively studied,and its contribution to the progression of cancers through suppressing senescence and promoting epithelial-mesenchymal transition has been *** reports on the role of TBX3 in gastric cancers have implied its involvement in gastric *** its pivotal role in the initiation and progression of cancers,TBX3 could be a promising therapeutic target for gastric cancers.