Comprehensive review on endoscopic ultrasound-guided tissue acquisition techniques for solid pancreatic tumor

作     者：Sakue Masuda Kazuya Koizumi Kento Shionoya Ryuhei Jinushi Makomo Makazu Takashi Nishino Karen Kimura Chihiro Sumida Jun Kubota Chikamasa Ichita Akiko Sasaki Masahiro Kobayashi Makoto Kako Uojima Haruki 

作者机构：Department of GastroenterologyShonan Kamakura General HospitalKanagawa 247-8533Japan Department of GastroenterologyInternal MedicineKitasato University School of MedicineKanagawa 252-0375Japan 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2023年第29卷第12期

页      面：1863-1874页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Endoscopic ultrasound-guided fine needle biopsy Endoscopic ultrasoundguided tissue acquisition Personalized medicine Genomic profiling test Pancreatic cancer Puncture procedure 

摘      要：Pancreatic ductal adenocarcinoma is speculated to become the second leading cause of cancer-related mortality by 2030,a high mortality rate considering the number of *** and chemotherapy are the main treatment options,but they are burdensome for patients.A clear histological diagnosis is needed to determine a treatment plan,and endoscopic ultrasound(EUS)-guided tissue acquisition(TA)is a suitable technique that does not worsen the cancer-specific prognosis even for lesions at risk of needle tract *** the development of personalized medicine and precision treatment,there has been an increasing demand to increase cell counts and collect specimens while preserving tissue structure,leading to the development of the fine-needle biopsy(FNB)***-FNB is rapidly replacing EUS-guided fine-needle aspiration(FNA)as the procedure of choice for EUS-TA of pancreatic ***,EUS-FNA is sometimes necessary where the FNB needle cannot penetrate small hard lesions,so it is important clinicians are familiar with *** these recent developments,we present an up-to-date review of the role of EUS-TA in pancreatic ***,technical aspects,such as needle caliber,negative pressure,and puncture methods,for obtaining an adequate specimen in EUS-TA are discussed.