Commentary:Acute psychological stress redistributed leukocytes via distinct brain circuits

作     者：Yan-Ping Wu Rong-Rong He Yan-Ping Wu;Rong-Rong He

作者机构：Guangdong Engineering Research Center of Chinese Medicine&Disease SusceptibilityJinan UniversityGuangzhou 510632China School of Traditional Chinese MedicineJinan UniversityGuangzhou 510632China International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education(MOE)College of PharmacyJinan UniversityGuangzhou 510632China Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs ResearchCollege of PharmacyJinan UniversityGuangzhou 510632China 

出 版 物：《Acta Pharmaceutica Sinica B》 (药学学报（英文版）)

年 卷 期：2022年第12卷第12期

页      面：4522-4524页

核心收录：

学科分类：0710[理学-生物学] 1007[医学-药学(可授医学、理学学位)] 07[理学] 071006[理学-神经生物学] 

基　　金：This work was supported by the National Natural Science Foundation of China(No.82125038,82004231) Guangdong Basic and Applied Basic Research Fund(No.2020A1515110388,China) GDUPS(2019,China). 

主　　题：Acute psychological stress Peripheral leukocytes HPA axis CXCL1 

摘      要：It is commonly known that psychological stress affects immunity through the nervous system,but the specific stress networks between brain and peripheral leukocytes,or their relationship with disease initiation or progression have yet to been delineated.A recent study by Poller and his colleagues1 propose an innovative perspective that distinct brain circuits rapidly manipulate a large-scale whole-body re-distribution of leukocytes(neutrophils,monocytes,lymphocytes)during psychological stress.