Impact of Multidisciplinary Collaborative Intervention on Isolation Implementation in Prevention and Control of Multi-drug Resistance Infection

作     者：Ying WANG Xin-ping ZHANG Xiao-quan LAI Xue-mei WANG Ying WANG;Xin-ping ZHANG;Xiao-quan LAI;Xue-mei WANG

作者机构：Naning Drum Tower Hospital Affiated to Nanjing University Medical SchoolNanjing210008China School of Medicine and Health ManagementTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China Department of Nosocomial Infection ManagementTongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China 

出 版 物：《Current Medical Science》 (当代医学科学（英文）)

年 卷 期：2023年第43卷第1期

页      面：198-205页

核心收录：

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1001[医学-基础医学(可授医学、理学学位)] 10[医学] 

基　　金：supported by the National Natural Science Foundation of China(No.71473098). 

主　　题：multidisciplinary collaborative intervention issuance of isolation orders multidrug-resistant organism infection and colonization isolation implementation rate 

摘      要：Objective Contact precautions,especially the initiation of isolation,are important measures to prevent and control multidrug-resistant organisms(MDROs).However,the implementation in clinical practice remains weak.This study aimed to analyze the impact of multidisciplinary collaborative intervention on isolation implementation in multidrug-resistant infection,and determine the factors that affect the implementation of isolation measures.Methods A multidisciplinary collaborative intervention related to isolation was conducted at a teaching tertiary hospital in central China on November 1,2018.The information of 1338 patients with MDRO infection and colonization at 10 months before and after the intervention was collected.Then,the issuance of isolation orders was retrospectively analyzed.Univariate analysis and multivariate logistic regression analysis were performed to analyze the factors that affected the isolation implementation.Results The overall issuance rate of isolation orders was 61.21%,which increased from 33.12%to 75.88%(P0.001)after the implementation of the multidisciplinary collaborative intervention.The intervention(P0.001,OR=0.166)was a promoting factor for the issuance of isolation orders,in addition to the length of stay(P=0.004,OR=0.991),department(P=0.004),and microorganism(P=0.038).Conclusion The isolation implementation remains far lower than policy standards.Multidisciplinary collaborative interventions can effectively improve the compliance to isolation measures implemented by doctors,thereby promoting the standardized management of MDROs,and providing reference for further improving the quality of hospital infection management.